How to complete 'The Final Puzzle' in Resident Evil Requiem

"The Final Puzzle" in Resident Evil Requiem asks you to "let the sweet pair hear the voice," but the actual solution is lengthy and specific: you must collect The Girl's Severed Hand, learn a few astronomy distances, flush a toilet eight times, and run through several story beats across one or more playthroughs.

You should begin from a save before the meat grinder sequence in the Care Center basement, and be prepared that completing the challenge in chronological order may require replaying large sections of the game. Start by progressing from the Inspection room into the Processing room in the Basement (you'll need two joint plugs and the Forklift key).

Wait 15 minutes as corpses drop into the bloody water until the area can be drained, then descend the ladder to trigger the meat grinder section; avoid killing enemies outright and immobilize them by shooting legs. After finishing the Basement, take the Severed Hand found beside the elevator to a Blood Analyzer in the Blood Lab and analyze it.

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