NFL Schedule Release 2025 Preview: The Most Anticipated Matchups of the Season

The NFL schedule release is like Christmas in May for football fans—except instead of presents, we get a fresh batch of overreactions, conspiracy theories, and way too much excitement over when our team plays the Jaguars. But hey, we’re not complaining. The 2025 NFL schedule is about to drop, and with it comes a whole new wave of must-see games, revenge narratives, and potential Super Bowl previews. So, while we wait for the official dates (and the inevitable meltdowns from fans who think a Week 4 bye is a "schedule loss"), let’s break down the most anticipated matchups of the 2025 season. 1. Patrick Mahomes vs. Josh Allen (Again… Because the NFL Loves Drama) Potential Matchup: Chiefs vs. Bills At this point, the NFL might as well just pencil in Chiefs vs. Bills as a prime-time game every year. Mahomes vs. Allen has become the league’s new Manning vs. Brady—except with more Hail Marys and way more memes. Will this finally be the year Buffalo gets over the hump? Or will Mahomes add another soul-crushing playoff dagger to his collection? Either way, this game is guaranteed to be an instant classic (and probably decided by a last-second field goal because, well, Buffalo things). 2. The Caleb Williams Show Comes to Lambeau Potential Matchup: Bears vs. Packers Rookie QB hype meets historic rivalry. Caleb Williams, the Bears’ shiny new franchise hope, will get his first taste of the NFL’s oldest feud—and Packers fans will be waiting. If Chicago’s front office did their job (big if), Williams could turn this into the next great QB duel with Jordan Love. If not? Well… at least Bears fans are used to disappointment. 3. The Harbaugh Bowl: Jim vs. John Potential Matchup: Chargers vs. Ravens The Harbaugh brothers coaching against each other is always must-watch TV, but now there’s an extra layer: Jim’s Chargers are rebuilding, while John’s Ravens are perennial contenders. Will Jim’s aggressive style catch his brother off guard? Or will Lamar Jackson do Lamar Jackson things and turn this into a highlight reel? Either way, expect at least one meme-worthy sideline meltdown. 4. Joe Burrow’s Revenge Tour Potential Matchup: Bengals vs. Chiefs Joe Burrow vs. Patrick Mahomes is becoming one of the NFL’s best QB rivalries, and after another playoff heartbreak in 2024, Burrow will be looking for payback. The real question: Will Ja’Marr Chase roast the Chiefs’ secondary again, or will Chris Jones remind everyone why he’s the most feared pass rusher in football? 5. The Return of Aaron Rodgers (For Real This Time… Maybe?) Potential Matchup: Jets vs. Packers Assuming Rodgers doesn’t retire to do another darkness retreat, his return to Lambeau Field will be must-watch TV. The Packers’ new era (Jordan Love & Co.) vs. the guy who held the keys for 15 years? Bonus drama: If the Jets are actually good this time, this could be a playoff preview. If not? Well, at least we’ll get some great Rodgers post-game pressers.